The absence of NIPA2 enhances neural excitability through BK (big potassium) channels.

Na-Na LiuHan XieWen-Shu Xiang-WeiKai GaoTian-Shuang WangYu-Wu Jiang

Published in: CNS neuroscience & therapeutics (2019)

The results indicate that the absence of NIPA2 enhances neural excitability through BK channels. Zonisamide is probably a potential treatment for NIPA2 mutation-induced epilepsy, which may provide a basis for the development of new treatment strategies for epilepsy.

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