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ErbB2-driven downregulation of the transcription factor Irf6 in breast epithelial cells is required for their 3D growth.

Iman Aftab KhanByong Hoon YooMichael McPheeOlivier MassonAlexi SuretteKelly Dakin-HacheTallal YounisGillian BethuneKirill V Rosen
Published in: Breast cancer research : BCR (2018)
We have demonstrated that ErbB2 blocks anoikis of breast epithelial cells by downregulating Irf6.
Keyphrases
  • transcription factor
  • tyrosine kinase
  • dendritic cells
  • signaling pathway
  • dna binding