Methylphenidate administration promotes sociability and reduces aggression in a mouse model of callousness.

Francesca ZorattoFrancesca FranchiSimone MacrìGiovanni Laviola

Published in: Psychopharmacology (2019)

Although our data support the notion that MPH may contribute to the management of excess aggression in CD patients, additional studies shall identify specific treatments to target the callousness domain. The latter, unaffected by MPH in our experimental model, demands focused consideration whereby it constitutes a specifier associated with a worse prognosis.

Keyphrases

mouse model
end stage renal disease
ejection fraction
newly diagnosed
attention deficit hyperactivity disorder
prognostic factors
peritoneal dialysis
electronic health record
patient reported outcomes
nk cells