Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer.

Nele LoretNiels VandammeJordy De ConinckJoachim TaminauKato De ClercqGillian BlanckeSven JonckheereSteven GoossensKelly LemeireSofie De PrijckKevin VerstaenRuth SeurinckJo Van DorpeSteven WeyersHannelore G Denys Koen K van de VijverBart N LambrechtPhilippe Tummers Yvan Saeys Geert Berx

Published in: Molecular cancer research : MCR (2022)

The newly characterized differences between ascitic and solid cancer cells before and after chemotherapy could inform novel treatment strategies for metastatic HGSOC.

Keyphrases

high grade
low grade
locally advanced
squamous cell carcinoma
small cell lung cancer
public health
gene expression
transcription factor
heat shock