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Performance of two commercially available BCR-ABL1 quantification assays that use an international reporting scale.

Soo Hyun SeoSeung Jun LeeSeungman ParkMin Jin KimJi Yoon SongEun Kyung RaSung Im ChoHyun Kyung KimMan Gil YangJi Yeon KimSung Sup ParkMoon-Woo Seong
Published in: Clinical chemistry and laboratory medicine (2017)
Two commercially available IS-based BCR-ABL1 assays showed an overall good quantitative correlation. It should be taken into consideration that each assay tended to produce higher values than the other, depending on the BCR-ABL1 subtypes, suggesting that a separate conversion factor for each subtype can be more helpful when BCR-ABL1 transcript levels are converted into IS.
Keyphrases
  • chronic myeloid leukemia
  • tyrosine kinase
  • high throughput
  • acute lymphoblastic leukemia
  • high resolution
  • rna seq
  • adverse drug