Tibial Cortex Transverse Transport Facilitates Severe Diabetic Foot Wound Healing via HIF-1α-Induced Angiogenesis.

Jie LiuXiajie HuangHongjie SuJie YuXinyu NieKaibing LiuWencong QinYongxin ZhaoYongfeng SuXiaocong KuangDi ChenWilliam Weijia LuYan ChenQikai Hua

Published in: Journal of inflammation research (2024)

TTT enhanced neovascularization and perfusion at the hindlimb and accelerated healing of the severe DFUs. The underlying mechanism is related to HIF-1α-induced angiogenesis.

Keyphrases

endothelial cells
high glucose
wound healing
vascular endothelial growth factor
drug induced
diabetic rats
early onset
total knee arthroplasty
magnetic resonance imaging
computed tomography