Familial Mediterranean fever-associated infertility and underlying factors.

Nuh AtasBerkan ArmaganErdal BodakciHasan SatisAlper SariNazife Sule Yasar BilgeReyhan Bilici SalmanGozde Kubra YardımcıHakan BabaogluLevent KilicMehmet Akif OzturkBerna GokerSeminur HaznedarogluTimucin KasifogluUmut KalyoncuAbdurrahman Tufan

Published in: Clinical rheumatology (2019)

Disease severity, FMF disease onset < 20 years, colchicine nonresponse, and female sex were found to be the independent predictors of infertility. The value of effective therapeutic interventions must be determined to treat infertility in these patients.Key Points•The prevalence of infertility increased in female patients with FMF.• Female sex, FMF disease onset < 20 years, disease severity, and colchicine nonresponse were risk factors for FMF-associated infertility.• With effective treatment of FMF, reversal of infertility was observed in five patients.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
peritoneal dialysis
physical activity
type diabetes
metabolic syndrome
risk factors
early onset
patient reported
skeletal muscle