A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin.

Luis G LealClive HoggartMarjo-Riitta JarvelinKarl-Heinz HerzigMichael J E Sternberg Alessia David

Published in: Molecular genetics & genomic medicine (2020)

The new PRS has a better predictive role in identifying HC of polygenic origin compared to the currently available method and can better stratify patients into diagnostic and therapeutic algorithms.

Keyphrases

end stage renal disease
newly diagnosed
machine learning
prognostic factors
peritoneal dialysis
deep learning
early onset
patient reported outcomes
patient reported