DNA Methylation of LRRC3B: A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients.

Yichen GuoRuyang ZhangSipeng ShenYongyue WeiSebastian Moran SalamaThomas FleischerMaria Moksnes BjaanæsAnna KarlssonMaria PlanckLi SuZhaozhong Zhu Johan Staaf Åslaug HellandManel EstellerDavid Chistopher Christiani

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2018)

We provide evidence of plausibility for building biomarkers on DNA methylation of LRRC3B for OS of early-stage NSCLC, thus filling a gap between previous in vitro studies and clinical applications.

Keyphrases

early stage
dna methylation
genome wide
gene expression
small cell lung cancer
sentinel lymph node
single cell
cell therapy
advanced non small cell lung cancer
case control
copy number
squamous cell carcinoma
lymph node
mesenchymal stem cells
brain metastases
bone marrow