Left ventricular anatomy in obstructive hypertrophic cardiomyopathy: beyond basal septal hypertrophy.
Uxio HermidaDavid StojanovskiBetty RamanRina ArigaAlistair A YoungValentina CarapellaGerry Carr-WhiteElena LukaschukStefan K PiechnikChristopher M KramerMilind Y DesaiWilliam S WeintraubStefan NeubauerHugh C WatkinsPablo LamataPublished in: European heart journal. Cardiovascular Imaging (2022)
LV anatomy underpinning oHCM consists of basal septal hypertrophy, apical dilatation, LV lengthening, and LVOT inward remodelling. Differences between oHCM cases at rest and stress, as well as the relationship between LV phenotype and genotype, suggest different mechanisms for LVOTO. Proposed Z-scores render an opportunity of redefining management strategies based on the relationship between LV anatomy and LVOTO.