Login / Signup

ThyroSeq overview on indeterminate thyroid nodules: An institutional experience.

Sam SirotnikovChristopher C GriffithDaniel J LubinChao ZhangNabil F SabaDehong LiAmanda KornfieldAmy ChenQiuying Shi
Published in: Diagnostic cytopathology (2024)
ThyroSeq v3 effectively stratifies the ROM in indeterminate thyroid nodules based on specific genetic alterations, guiding appropriate surgical management. Notably, the BRAFV600E/high-risk group and RAS-like groups exhibited ROM of 100% and 77.5%, respectively, with promising predictive accuracy (PPV of 78.2% and NPV of 75.9%).
Keyphrases
  • fine needle aspiration
  • genome wide
  • wild type
  • copy number
  • gene expression