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Verification of mesenchymal stem cell injection therapy for interstitial cystitis in a rat model.

Jae Wook ChungSo Young ChunEun Hye LeeYun-Sok HaJun Nyung LeePhil Hyun SongEun Sang YooTae Gyun KwonSung Kwang ChungBum Soo Kim
Published in: PloS one (2019)
Regardless of the cell source, human tissue-derived mesenchymal SCs regenerated damaged bladder tissue, promoted functional recovery and inhibited inflammatory cell accumulation in an IC rat model; particularly, USC had the highest inhibitory effect on inflammation. Additionally, direct USC injection into the bladder submucosa was expected to have the best therapeutic effect, which will be an important factor for clinical applications in the future.
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