Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells.

Min-Kyoung ShinYong-Deok JeonJong-Sik Jin

Published in: Journal of the science of food and agriculture (2018)

Enterodiol inhibited the growth of CRC cells by controlling the MAPK signaling pathway involved in proliferation and apoptosis. These results demonstrate that END has an apoptotic effect in CRC cells. © 2018 Society of Chemical Industry.

Keyphrases

cell cycle arrest
signaling pathway
induced apoptosis
cell death
pi k akt
endoplasmic reticulum stress
oxidative stress
epithelial mesenchymal transition
anti inflammatory