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Adherence to Anti-Malarial Treatment in Malaria Endemic Areas of Bangladesh.

Mohammad Sharif HossainMohammad Abdul MatinNur-E Naznin FerdousAnamul HasanSaiful Arefeen SazedAmit Kumer NeogiSumit ChakmaMd Atiqul IslamAfsana Alamgir KhanMd Ekramul HaqueShayla IslamMd Nazmul IslamWasif Ali KhanMd Akramul IslamRashidul HaqueMohammad Shafiul Alam
Published in: Pathogens (Basel, Switzerland) (2023)
Ensuring adherence to antimalarial treatment is crucial for achieving a radical cure and elimination of malaria, especially in hard-to-reach areas. We conducted this study to assess the current scenario of drug adherence in four endemic sub-districts of Bangladesh. Among 110 enrolled participants, 70% were mono-infected with Plasmodium falciparum and the remaining 30% with P. vivax . The overall treatment adherence frequency was 92.7% (95% CI: 83.0-96.3%). A total of eight participants were found to be nonadherent to treatment and all of them were from Bandarban. Level of nonadherence was equally observed in two age groups: 11-17 and 18+ years. However, male participants ( n = 6) were found to be more nonadherent than females ( n = 2). Among 7.3% with nonadherence to treatment, a single participant with P. falciparum mono-infection refused to take medication and became nonadherent. Remaining participants stated that they were feeling well and going to work, thus leaving treatment course uncompleted. Although overall compliance with malaria medication seems good, a gradual increase in noncompliance to P. vivax malaria treatment suggests that the National Malaria Elimination Program must be enhanced and monitored to fulfil the projected malaria elimination goal before 2030 from Bangladesh.
Keyphrases
  • plasmodium falciparum
  • healthcare
  • emergency department
  • type diabetes
  • metabolic syndrome
  • replacement therapy