CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.

Dörte LodkaMaria ZschummelMario BunseAnthony RousselleJanis SonnemannRalph KettritzUta E HöpkenAdrian Schreiber

Published in: Annals of the rheumatic diseases (2024)

Our proof-of-principle study may encourage further exploration of CAR T cells as a treatment for ANCA-vasculitis patients with the goal of drug-free remission.

Keyphrases

acute kidney injury
induced apoptosis
cell cycle arrest
cardiac surgery
drug induced
high glucose
endoplasmic reticulum stress
oxidative stress
disease activity
rheumatoid arthritis
emergency department
combination therapy
replacement therapy
nk cells