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Comparative analysis of spatial-temporal patterns of human metapneumovirus and respiratory syncytial virus in Africa using genetic data, 2011-2014.

John W OketchEverlyn KamauJames R OtienoAnthony MwemaClement LewaEverlyne IsoeD James NokesCharles N Agoti
Published in: Virology journal (2021)
The spatial clustering patterns of viral sequences and genotype dominance patterns observed in our analysis suggests strong regional links and predominant local transmission. The geographical clustering further suggests independent introduction of HMPV and RSV variants in Africa from the global pool, and local regional diversification.
Keyphrases
  • respiratory syncytial virus
  • endothelial cells
  • single cell
  • copy number
  • sars cov
  • rna seq
  • electronic health record
  • dna methylation
  • gene expression
  • machine learning
  • data analysis
  • respiratory tract