Evolution of brain MRI lesions in paediatric myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and its relevance to disease course.

Omar A Abdel-MannanDimitrios ChampsasCarmen TurVanessa LeeSharmila ManivannanHaroon UsmanAlison SkippenIshita DesaiManali ChitreRob ForsythRachel KneenDipak RamSithara RamdasThomas RossorSiobhan WestSukhvir WrightJacqueline PalaceEvangeline WassmerCheryl HemingwayMing J LimKshitij MankadOlga CiccarelliYael Hacohennull null

Published in: Journal of neurology, neurosurgery, and psychiatry (2023)

These striking differences in lesion dynamics between MOGAD and MS suggest greater potential to repair. Early treatment with steroids and plasma exchange is associated with reduced likelihood of new lesions.

Keyphrases

white matter
magnetic resonance imaging
intensive care unit
multiple sclerosis
resting state
computed tomography
functional connectivity
human health
cerebral ischemia
subarachnoid hemorrhage