Antitumor Effects of Self-Assembling Peptide-Emodin in situ Hydrogels in vitro and in vivo.

Weipeng WeiJianhua TangHongfang LiYongsheng HuangChengchen YinDan LiFushang Tang

Published in: International journal of nanomedicine (2021)

Our results demonstrated that RADA16-I has the potential to be a carrier for the hydrophobic drug EM and can effectively improve the delivery of hydrophobic antitumor drugs with enhanced antitumor effects and reduced toxic effects of the drugs on normal cells and tissues.

Keyphrases

induced apoptosis
ionic liquid
gene expression
cell cycle arrest
drug delivery
drug induced
emergency department
extracellular matrix
hyaluronic acid
endoplasmic reticulum stress
risk assessment
tissue engineering
human health