Serum cardiovascular risk biomarkers in pre-pubertal obese children.
Albane B R MaggioNathalie J Farpour-LambertYacine AggounKatia GalanFabrizio MontecuccoFrançois MachMaurice BeghettiPublished in: European journal of clinical investigation (2018)
The usefulness of serum biomarkers for the detection of cardiovascular diseases is not well established in children. In our population, MMP-8 concentration was higher in hypertensive children. Furthermore, behavioural interventions resulted in a paradoxical increase in some biomarkers in children, with potentially beneficial effects detected with CCL2 changes. Caution should be taken when using nonspecific serum biomarkers for the clinical monitoring of children with obesity.