Drug Resistance Mutations Among South African Children Living With HIV on WHO-recommended ART Regimens.
Stephanie HackettChloe A TeasdaleSherri PalsAnthony MuttitiMary MogashoaJoy ChangClement ZehArtur RamosEmilia D RivadeneiraJoshua DeVosKatrina SleemanElaine J AbramsPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
High levels of NNRTI and NRTI DRMs among CLHIV receiving ABC/3TC/LPV/r suggests a lasting impact of failed mother-to-child transmission interventions on DRMs. However, drug susceptibility analysis reveals that CLHIV with detectable viremia on ABC/3TC/LPV/r are more likely to have maintained at least 2 effective agents on their current HIV regimen than those on ABC/3TC/EFV.