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Clinical and biological relevance of genetic alterations in pediatric T-cell acute lymphoblastic leukemia in Taiwan.

Ting-Chi YehDer-Cherng LiangHsi-Che LiuTang-Her JaingShih-Hsiang ChenJen-Yin HouChao-Ping YangYing-Jung HuangHsien-Wen YaoTing-Yu HuangTung-Huei LinLee-Yung Shih
Published in: Pediatric blood & cancer (2018)
The present study showed that the frequencies of genetic alterations in Taiwanese children with T-ALL differed considerably from those reported in Western countries. PHF6 mutation/deletion was an independently adverse predictor.
Keyphrases
  • acute lymphoblastic leukemia
  • genome wide
  • young adults
  • copy number
  • south africa
  • allogeneic hematopoietic stem cell transplantation