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Diversity-oriented synthesis derived indole based spiro and fused small molecules kills artemisinin-resistant Plasmodium falciparum.

Akshaykumar NayakHimani SaxenaChandramohan BathulaTarkeshwar KumarSouvik BhattacharjeeSubhabrata SenAshish Gupta
Published in: Malaria journal (2021)
Overall the compounds 2 and 3 identified in this study shows promising anti-plasmodial activity that can kill both artemisinin-sensitive and artemisinin-resistant strains of P. falciparum.
Keyphrases
  • plasmodium falciparum
  • escherichia coli