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A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies.

Marilia TakadaMaciej ParysEmmalena Gregory-BrysonPaulo Vilar SaavedraMatti KiupelVilma Yuzbasiyan-Gurkan
Published in: BMC cancer (2018)
In the present study we demonstrated that a novel canine histiocytic sarcoma cell line presents a valuable tool to evaluate novel treatment approaches. The neoplastic cell line favorably responded to dasatinib, which represents a promising anticancer strategy for the treatment of this malignancy in dogs and similar disorders in humans.
Keyphrases
  • combination therapy
  • replacement therapy
  • chronic myeloid leukemia