p53 Function and Dysfunction in Human Health and Diseases.
Gabriella D'OraziPublished in: Biomolecules (2023)
The p53 protein is a sequence-specific DNA-binding transcription factor that, in response to stressful stimuli, regulates gene expression related to multiple cellular functions including, but not limited to, cell cycle arrest, cell apoptosis, cell growth, DNA repair, cell metabolism, and the immune response [...].
Keyphrases
- dna binding
- dna repair
- human health
- transcription factor
- cell cycle arrest
- gene expression
- risk assessment
- immune response
- cell death
- dna damage
- pi k akt
- climate change
- dna methylation
- dna damage response
- cell proliferation
- single cell
- cell therapy
- amino acid
- oxidative stress
- dendritic cells
- signaling pathway
- toll like receptor
- bone marrow
- inflammatory response