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External Validation of the Colon Life Nomogram for Predicting 12-Week Mortality in Dutch Metastatic Colorectal Cancer Patients Treated with Trifluridine/Tipiracil in Daily Practice.

Patricia A H HamersG Emerens WensinkMaarten van SmedenGeraldine R VinkLidwien P SmabersRenee A LunenbergMiangela M LacléMiriam KoopmanAnne M MayJeanine M L Roodhart
Published in: Cancers (2022)
We demonstrated evident miscalibration of the Colon Life nomogram upon external validation, which hampers its use in clinical practice. We recommend conducting a study with a sufficiently large sample size to update the Colon Life nomogram or to develop a new model including QoL.
Keyphrases
  • metastatic colorectal cancer
  • lymph node metastasis
  • clinical practice
  • healthcare
  • primary care
  • squamous cell carcinoma
  • risk factors
  • quality improvement