Mild behavioral impairment is linked to worse cognition and brain atrophy in Parkinson disease.
Eun Jin YoonZahinoor IsmailAlexandru HanganuMekale KibreabTracy HammerJenelle CheethamIris KatholJustyna R SarnaDavide MartinoSarah FurtadoOury MonchiPublished in: Neurology (2019)
The impaired cognitive function over all domains and atrophy in the temporal area in the PD-MBI group are in line with posterior cortical circuit deficits in PD, which have been associated with a faster rate of progression to dementia. These initial results suggest that MBI might be an early and important marker for incident cognitive decline and dementia in patients with PD.