Epigenetic silencing of AATK in acinar to ductal metaplasia in murine model of pancreatic cancer.

Li-Yun DingYa-Chin HouI-Ying KuoTing-Yi HsuTsung-Ching TsaiHsiu-Wei ChangWei-Yu HsuChih-Chieh TsaoChung-Chen TianPo-Shun WangHao-Chen WangChung-Ta LeeYi-Ching WangSheng-Hsiang LinMichael W HughesWoei-Jer ChuangPei-Jung LuYan-Shen ShanPo-Hsien Huang

Published in: Clinical epigenetics (2020)

Epigenetic silencing of AATK regulates the cellular transdifferentiation, proliferation, and cell cycle progression in converting PDA-subtypes.

Keyphrases

cell cycle
dna methylation
cell proliferation
gene expression
signaling pathway