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Genomic analysis and prediction of genomic values for distichiasis in Staffordshire bull terriers.

Dina JørgensenErnst-Otto RopstadTheodorus MeuwissenFrode Lingaas
Published in: Canine medicine and genetics (2023)
Four genomic regions associated with distichiasis were discovered in the association analysis, suggesting that distichiasis in SBT is a complex trait involving numerous loci. The four associated regions need to be confirmed in an independent sample. We also used all 95 K SNPs for genomic prediction and showed that genomic prediction can be a helpful tool in selective breeding schemes at breed level aiming at reducing the prevalence of distichiasis in SBTs in the future, even if the predictive value of single dogs may be low.
Keyphrases
  • copy number
  • genome wide
  • dna methylation
  • gene expression
  • current status