Characteristics of homologous recombination repair pathway genes mutation in ovarian cancers.

Zong-Bi YiMin ChenShaoxing SunChunxu YangZijie MeiHui YangQingming XiangHui Qiu

Published in: Cancer innovation (2022)

HRR pathway somatic mutations are common in Chinese patients with ovarian cancer. HRR pathway somatic mutations were associated with improved sensitivity to platinum-based chemotherapy. Large-scale prospective studies are needed to verify our findings.

Keyphrases

dna damage
copy number
radiation therapy
young adults
bioinformatics analysis