Clinical Evaluation of Tavocept to Decrease Diuresis Time and Volume in Dogs with Bladder Cancer Receiving Cisplatin.
Carolyn J HenryB K FlesnerS A BechtelJ N BryanD J TateK A SeltingJ C LattimerM E BryanL GrubbF HausheerPublished in: Journal of veterinary internal medicine (2017)
Tavocept decreased the required diuresis time with cisplatin from > 6 hours to 90 minutes, while also decreasing occurrence of azotemia. Survival time was comparable, but the response rate was inferior to an historical comparator group. Further evaluation in other tumors susceptible to platinum agents is warranted.
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