Towards Ni(II) complexes with spin switches for 19F MR-based pH sensing.
Da XieLauren E OhmanEmily L QuePublished in: Magma (New York, N.Y.) (2018)
The significant difference in the chemical shift and relaxation times between NiL1 and NiL2 allowed selective imaging of these species using 19F MRI. While NiL1 and NiL2 were not stable to acidic environments, this report lays the framework for development of improved ligand scaffolds that stably coordinate Ni(II) in acidic aqueous solution and act as agents for ratiometric pH mapping by 19F MRI.