Identification of risk features for complication in Gaucher's disease patients: a machine learning analysis of the Spanish registry of Gaucher disease.

Marcio M Andrade-CamposLaura López de FrutosJorge J CebollaIrene Serrano-GonzaloBlanca Medrano-EngayMercedes Roca-EspiauBeatriz Gomez-BarreraJorge Pérez-HerediaDavid IniguezPilar Giraldo

Published in: Orphanet journal of rare diseases (2020)

Our work confirms previous observations, highlights the importance of early diagnosis and therapy and identifies new risk features such as high IgA and IgG levels for long-term complications.

Keyphrases

machine learning
end stage renal disease
ejection fraction
replacement therapy
newly diagnosed
peritoneal dialysis
artificial intelligence
genome wide
stem cells
mesenchymal stem cells
patient reported outcomes
dna methylation
smoking cessation
cell therapy
bioinformatics analysis