Virulence gene polymorphisms in Shandong Helicobacter pylori strains and their relevance to gastric cancer.
Zhijing XueWeijia LiHailing DingFengyan PeiJiangzhong ZhangYanan GongRuyue FanFang WangYoujun WangQing ChenYanran LiXinyu YangYan ZhengGuohai SuPublished in: PloS one (2024)
CagA proteins possessing CM motif pattern D were more frequently observed in patients with GC (P < 0.01), implying a potentially higher virulence of CM motif pattern D than the other CM motif patterns. Moreover, a strong positive association was identified between the vacA c1 genotype and GC, indicating that the vacA c1 genotype is a robust risk indicator for GC among male patients aged ≥55 years in Shandong.
Keyphrases
- helicobacter pylori
- escherichia coli
- helicobacter pylori infection
- pseudomonas aeruginosa
- staphylococcus aureus
- end stage renal disease
- newly diagnosed
- ejection fraction
- biofilm formation
- antimicrobial resistance
- chronic kidney disease
- gas chromatography
- patient reported outcomes
- candida albicans
- tandem mass spectrometry