Login / Signup

Insulin and osteocalcin: further evidence for a mutual cross-talk.

Francesco L BilottaBiagio ArcidiaconoSebastiano MessineoMarta GrecoEusebio ChiefariDomenico BrittiTomoko NakanishiDaniela Patrizia FotiAntonio Brunetti
Published in: Endocrine (2017)
Our results further support the existence of an endocrine axis between bone, where osteocalcin is produced, and pancreatic β-cells, and add new insights into the molecular details of this relationship. These findings may contribute to the understanding of osteocalcin regulation and its role in metabolism.
Keyphrases
  • induced apoptosis
  • type diabetes
  • cell cycle arrest
  • bone mineral density
  • oxidative stress
  • cell death
  • glycemic control
  • postmenopausal women
  • bone loss
  • skeletal muscle