A novel chondrocyte sheet fabrication using human-induced pluripotent stem cell-derived expandable limb-bud mesenchymal cells.

Tomoka TakaoMasato SatoYuki FujisawaEriko ToyodaDaisuke YamadaYukio HitsumotoEiji NakataToshifumi OzakiTakeshi Takarada

Published in: Stem cell research & therapy (2023)

The present study is the first to report the chondrocyte sheet fabrication with hiPSC-derived cell source. hiPSC-derived ExpLBM would be a promising cell source for cell sheet technology in articular cartilage regenerative medicine.

Keyphrases

single cell
cell therapy
stem cells
induced apoptosis
bone marrow
mesenchymal stem cells
cell proliferation
signaling pathway
cell death