Plasma Extracellular Vesicles Derived from Pediatric COVID-19 Patients Modulate Monocyte and T Cell Immune Responses Based on Disease Severity.

Pınar Gur Cetinkaya Irem Fatma Abras Irem Evcili Tugçe Yildirim Yasemin Ceylan Fehime Kara Eroğlu Başak Kayaoglu Emre Mert İpekoglu Ayşegul Akarsu Muzaffer Yıldırım Tamer Kahraman Ali Bulent Cengiz Ümit Murat Şahiner Bulent Enis Sekerel Yasemin Özsürekci Ozge Soyer İhsan GÜrsel

Published in: Immunological investigations (2024)

This study reveals the complex relationship between immunological responses and EV-mediated effects, emphasizing the impact of COVID-19 severity. We highlight the potential role of plasma-derived EVs in early-stage immunosuppression in severe COVID-19 patients.

Keyphrases

sars cov
early stage
immune response
coronavirus disease
dendritic cells
early onset
endothelial cells
toll like receptor
peripheral blood
radiation therapy
sentinel lymph node