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Long-acting somatostatin analogue treatments in autosomal dominant polycystic kidney disease and polycystic liver disease: a systematic review and meta-analysis.

Joshua GriffithsMark T MillsAlbert C M Ong
Published in: BMJ open (2020)
The available RCT data show improvement in TLV with somatostatin analogue treatment. There was no benefit to TKV or eGFR in patients with ADPKD, while being associated with various side effects. Further studies are needed to assess potential benefit in reducing cyst burden in patients with PLD.
Keyphrases
  • polycystic kidney disease
  • small cell lung cancer
  • neuroendocrine tumors
  • epidermal growth factor receptor
  • tyrosine kinase
  • electronic health record
  • big data
  • combination therapy
  • deep learning
  • replacement therapy