Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation.

Yan ZhangYifei QiZijun JiaYiming LiLiqi WuQing-Bing ZhouFengqin Xu

Published in: Chinese medicine (2024)

This study combining network pharmacology, molecular biology, and animal experiments showed that ZCHP can alleviate AS by suppressing the TNF/NF-κB axis and M1 macrophage polarization.

Keyphrases

molecular docking
molecular dynamics simulations
rheumatoid arthritis
signaling pathway
lps induced
oxidative stress
type diabetes
nuclear factor
toll like receptor