The presence of non-criteria manifestations negatively affects the prognosis of seronegative antiphospholipid syndrome patients: a multicenter study.
Gilberto Pires da RosaBernardo Sousa-PintoEster FerreiraOlga AraújoGiuseppe BarilaroPaulo BettencourtRicard CerveraGerard EspinosaPublished in: Arthritis research & therapy (2022)
SN-APS displayed more thrombosis recurrence, indefinite anticoagulation, and VKA use than controls without non-criteria manifestations. The presence of such features in patients with thrombosis and negative aPL may negatively impact their clinical course.