Association of the FGF4L2 retrogene with fibrocartilaginous embolic myelopathy in dogs.

Colleen EmbersicsDanika L BannaschKevin BatcherC Elizabeth BoudreauMolly ChurchAndrew MillerSimon R PlattJey KoehlerNatasha Jane Olby John H RossmeislDaniel RissiRobert GrahnJonas DonnerPeter J Dickinson

Published in: Journal of veterinary internal medicine (2023)

Study data based on genotypically and histopathologically defined cases support the historical observation that FCE is uncommon in chondrodystrophic dog breeds. FGF4 plays an important role in angiogenesis and vascular integrity; anatomical studies comparing chondrodystrophic and non-chondrodystrophic dogs might provide insight into the pathogenesis of FCE.

Keyphrases

spinal cord
endothelial cells
electronic health record
vascular endothelial growth factor
big data
case control
genetic diversity
artificial intelligence