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Oncoprotein HBXIP promotes tumorigenesis through MAPK/ERK pathway activation in non-small cell lung cancer.

Jun ZhangBei SunXianhui RuanXiukun HouJingtai ZhiXiangrui MengXiangqian ZhengMing Gao
Published in: Cancer biology & medicine (2021)
Taken together, our results showed that the HBXIP-MEK interaction promoted oncogenesis via the MAPK/ERK pathway, which may serve as a novel therapeutic target for cancers in which MAPK/ERK signaling is a dominant feature.
Keyphrases
  • signaling pathway
  • pi k akt
  • cell proliferation
  • machine learning
  • oxidative stress
  • deep learning
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  • neural network