Impact of metformin use on the cardiovascular effects of dipeptidyl peptidase-4 inhibitors: An analysis of Medicare claims data from 2007 to 2015.
Matthew J CrowleyMugdha N GokhaleVirginia PateTil StürmerJohn B BusePublished in: Diabetes, obesity & metabolism (2018)
Incidence rate differences in multiple CV outcomes appeared more favourable when DPP-4 inhibitor initiation occurred in the presence of metformin, suggesting a possible interaction between DPP-4 inhibitors and metformin.