Construction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction.
Lingliang LongXiangqi YuanSiyu CaoYuanyuan HanWeiguo LiuQian ChenAihua GongWang KunPublished in: Chemical communications (Cambridge, England) (2019)
A novel fluorescent probe XQ-1 for selectively detecting 1O2 on the basis of a two-step cascade reaction has been rationally constructed. The probe responded to 1O2 not only showing a high sensitivity, but also displaying a large concentration range, which means that the probe can be used as a powerful tool to monitor the efficacy of PDT toward cancer and concurrently track the adverse effects on healthy cells.
Keyphrases
- living cells
- fluorescent probe
- induced apoptosis
- papillary thyroid
- cell cycle arrest
- photodynamic therapy
- squamous cell
- single molecule
- wastewater treatment
- endoplasmic reticulum stress
- quantum dots
- signaling pathway
- lymph node metastasis
- squamous cell carcinoma
- electron transfer
- cell proliferation
- cell death
- adverse drug