Diffusion MRI is valuable in brainstem glioma genotyping with quantitative measurements of white matter tracts.
Xiong XiaoNe YangGuocan GuXianyu WangZhuang JiangTian LiXinran ZhangLongfei MaPeng ZhangHongen LiaoDeling LiPublished in: European radiology (2023)
• Diffusion MRI has significant value in brainstem glioma H3K27M genotyping, and models with satisfactory performances were built. • Whole-tumor diffusion histogram features are useful in H3K27M genotyping, and quantitative measurements of white matter tracts are valuable as they have the potential to improve model performance. • The model combining the most discriminative diffusion MRI model and clinical variables can help make clinical decision.