Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.
James E BarrettAndrew FeberJavier HerreroMiljana TanicGareth A WilsonCharles SwantonStephan BeckPublished in: BMC bioinformatics (2017)
Detection and comparison of epialleles within multiple tumour regions enables phylogenetic analyses, identification of differentially expressed epialleles, and provides a measure of epigenetic heterogeneity. R code is available at github.com/james-e-barrett.