mTOR signaling pathway regulation HIF-1 α effects on LPS induced intestinal mucosal epithelial model damage.

Zeyong HuangWenbin TengLiuxu YaoKai XieSuqin HangRui HeYuhong Li

Published in: BMC molecular and cell biology (2024)

This study once again confirmed that HIF-1α alleviates LPS-induced mucosal epithelial model damage through P70S6K signalling pathway. It is of great value to explore whether HIF-2α plays crucial roles in the regulation of mucosal epithelial model functions in the future.

Keyphrases

lps induced
inflammatory response
signaling pathway
oxidative stress
endothelial cells
ulcerative colitis
pi k akt
induced apoptosis
endoplasmic reticulum stress