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Could giant viruses be considered as a biotechnological tool for preventing and controlling Acanthamoeba infections?

Ana Paula Correia CrispimMateus Sá Magalhães SerafimAdriana Oliveira CostaJonatas Santos Abrahao
Published in: Journal of applied microbiology (2024)
Mimivirus demonstrates a greater ability to inhibit A. castellanii encystment and excystment compared to commercial multipurpose contact lens solutions. Additionally, mimivirus is less toxic to MDCK cells than those commercial solutions. New studies utilizing in vivo models will be crucial for confirming safety and efficacy parameters.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • signaling pathway
  • genetic diversity