PhI(OTf)2 Does Not Exist (Yet)*.

null TaniaSevan D HoustonLachlan Sharp-BucknallTiffany B PoynderMohammad AlbayerJason L Dutton

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)

PhI(OTf)2 has been used for the past 30 years as a strong I(III) oxidant for organic and inorganic transformations. It has been reported to be generated in situ from the reactions of either PhI(OAc)2 or PhI=O with two equivalents of trimethylsilyl trifluoromethanesulfonate (TMS-OTf). In this report it is shown that neither of these reactions generate a solution with spectroscopic data consistent with PhI(OTf)2 , with supporting theoretical calculations, and thus this compound should not be invoked as the species acting as the oxidant for transformations that have been associated with its use.

Keyphrases

molecular dynamics
electronic health record
density functional theory
machine learning
big data
water soluble
genetic diversity
high frequency