Estimated impact of guidelines-based initiation of dual antihypertensive therapy on long-term cardiovascular outcomes in 1.1 million individuals.
Antonio CocaClaudio BorghiGeorge S StergiouIrfan KhanAlexandra KoumasJacques BlacherMohamed Abdel-MoneimPublished in: European heart journal. Cardiovascular pharmacotherapy (2024)
This study represents the first to investigate guidelines-based treatment in hypertensive patients and demonstrates the opportunity for considerable risk reduction by ensuring recommended dual therapy in clinical practice, particularly in the form of SPC with high persistence, relative to no treatment or monotherapy.