During the past 15 years, the advent of digital innovations has completely changed the dental practice. Tools like intraoral scanners, computer-aided design (CAD) and computer-aided manufacturing (CAM) are considered perfectly reliable and affordable, today. The use of these digital techniques greatly facilitates restorative and prosthetic treatment. It is particularly interesting to combine isolation under the rubber dam with digital impressions in adhesive restorative dentistry. In this article, a clinical protocol is given on the basis of a case for making a digital impression under the rubber dam.